HOUSTON (Jul. 12, 2022) – Dr. Joshua Shulman, Professor at Baylor College of Medicine, has been named the new Co-Director of the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital. The Duncan NRI is a premier neurological research institution and a destination for families seeking answers and treatments for rare and undiagnosed neurological conditions, as well as for more common neurodegenerative and neuropsychiatric disorders.
“Dr. Shulman is one of those rare physician-scientists who possess exquisite clinical skills, compassion, scholarship, and innovation in research,” said Dr. Huda Zoghbi, Director of the Duncan NRI, Howard Hughes Medical Institute Investigator, and distinguished service Professor at Baylor. “These attributes, combined with his leadership and dedication to mentoring the next generation of scientists, make him ideal for the Co-Director role at the Duncan NRI. I am thrilled to partner with him as we continue to move forward addressing devastating neurological disorders.”
Dr. Shulman succeeds Dr. John Swann as the Co-Director of the Duncan NRI and brings with him 25 years of experience as a neuroscientist and adult neurologist specializing in Parkinson’s, Alzheimer’s, and other neurodegenerative disorders. He completed his medical and research training at Harvard Medical School, Massachusetts General and Brigham and Women’s Hospitals, and Cambridge University in the U.K. He was recruited to Baylor and the Duncan NRI in 2012 and is now a Professor in the departments of Neurology, Molecular and Human Genetics, and Neuroscience at Baylor. He is also the founding Director of Baylor’s Center for Alzheimer’s and Neurodegenerative Diseases and holds the Huffington Foundation Endowed Chair for Parkinson’s Disease Research at the Duncan NRI and the Effie Marie Cain Chair in Alzheimer’s Disease Research at Baylor.
Using a multidisciplinary approach that integrates human genomic analyses with functional investigation in experimental animal models of neurodegenerative disease, Dr. Shulman and his team have made several important discoveries that have led to a better understanding of the genes and mechanisms involved in Alzheimer’s and Parkinson’s diseases. In recognition of his stellar contributions to neurology, he received the prestigious 2020 Derek Denny-Brown Young Neurological Scholar Award from the American Neurological Association.
“The Duncan NRI truly is a special place, with an unparalleled collaborative and cross-disciplinary approach that propels groundbreaking research on brain diseases affecting children and adults alike,” said Dr. Shulman. “The success of my research program over the last decade owes much to the Duncan NRI and I am proud to serve as its Co-Director. It is a privilege to represent and support my outstanding colleagues at the Duncan NRI and to learn from and work with Dr. Huda Zoghbi to further Duncan NRI’s mission.”
About Texas Children’s Hospital
Texas Children’s Hospital, a not-for-profit health care organization, is committed to creating a healthier future for children and women throughout the global community by leading in patient care, education and research. Consistently ranked as the best children’s hospital in Texas, and among the top in the nation, Texas Children’s has garnered widespread recognition for its expertise and breakthroughs in pediatric and women’s health. The hospital includes the Jan and Dan Duncan Neurological Research Institute; the Feigin Tower for Pediatric Research; Texas Children’s Pavilion for Women, a comprehensive obstetrics/gynecology facility focusing on high-risk births; Texas Children’s Hospital West Campus, a community hospital in suburban West Houston; and Texas Children’s Hospital The Woodlands, the first hospital devoted to children’s care for communities north of Houston. The organization also created Texas Children’s Health Plan, the nation’s first HMO for children; Texas Children’s Pediatrics, the largest pediatric primary care network in the country; Texas Children’s Urgent Care clinics that specialize in after-hours care tailored specifically for children; and a global health program that’s channeling care to children and women all over the world. Texas Children’s Hospital is affiliated with Baylor College of Medicine. For more information, go to www.texaschildrens.org. Get the latest news by visiting the online newsroom and Twitter at twitter.com/texaschildrens.
About Baylor College of Medicine
Baylor College of Medicine (www.bcm.edu) in Houston is recognized as a health sciences university and is known for excellence in education, research and patient care. It is ranked 22nd among medical schools for research and 17th for primary care by U.S. News & World Report. Baylor is listed 20th among all U.S. medical schools for National Institutes of Health funding and No. 1 in Texas. The Baylor pediatrics program ranked 7th among all pediatric programs, reflecting the strong affiliation with Texas Children’s Hospital where our faculty care for pediatric patients and our students and residents train. Nationally our physician assistant program was ranked 3rd in the health disciplines category and our nurse anesthesia program ranked 2nd. Located in the Texas Medical Center, Baylor has affiliations with seven teaching hospitals and jointly owns and operates Baylor St. Luke’s Medical Center, part of St. Luke’s Health. Currently, Baylor has more than 3,000 trainees in medical, graduate, nurse anesthesia, physician assistant, orthotics and genetic counseling as well as residents and postdoctoral fellows. Follow Baylor College of Medicine on Facebook (http://www.facebook.com/BaylorCollegeOfMedicine) and Twitter (http://twitter.com/BCMHouston).
Understanding Silver Price Trends in Melbourne: Factors, Trends, and Current Values
Silver, known for its diverse applications and intrinsic value, experiences fluctuations influenced by various factors.
Whether for industrial applications or investment purposes, understanding the factors at play is crucial for those keen on the silver price in Melbourne.
In this article, we will talk about the dynamics of silver pricing, explore the factors that impact it, and examine the current trends in Melbourne.
Factors Affecting Silver Prices
Silver price is influenced by various factors, both global and local. Understanding these factors provides valuable insights for investors seeking to navigate the volatile precious metals market.
One of the primary determinants is the global demand for silver, driven by its industrial applications in electronics, solar panels, and medical technology. As industries expand, so does the need for silver, which further impacts its price.
Moreover, the economic health of major nations, including Australia, plays a pivotal role. In times of economic uncertainty or major world crises, investors often turn to precious metals like silver as a safe-haven asset, causing an increase in demand and subsequently raising prices.
Opposite of that, periods of economic stability may witness a decrease in silver prices as investors diversify their investment portfolio.
Geopolitical factors also contribute to silver price fluctuations. Political tensions, trade disputes, and global events can create an atmosphere of uncertainty, prompting investors to turn to silver as a hedge against inflation and economic downturns.
Current Silver Price Trends in Melbourne
As of the latest market reports, the silver price in Melbourne is reflective of the global trends influencing precious metal values. The current silver price in Melbourne stands at AUD 36, demonstrating a rise of 2.22% in the past 6 months. This fluctuation aligns with the broader patterns observed in the international precious metals market.
As for the future value of silver, predictions are optimistic, with the silver price potentially rising to around AUD 53 in the first quarter of 2024, and moving to AUD 73 by 2025.
It’s important to note that silver prices are not solely dictated by global factors. Local market conditions, such as mining activity and silver demand within Australia, also contribute to the dynamics. Melbourne, as a key economic hub, often experiences unique market trends compared to other regions.
Impacts of Local Mining Activity
Australia, blessed with rich natural resources, is a significant player in the global silver market. The country’s mining activity, particularly in regions surrounding Melbourne, has a direct impact on local silver prices.
Changes in production levels, mining regulations, and exploration activities can influence the supply side, subsequently affecting prices in Melbourne.
Investor Sentiment and Silver Price Melbourne
Investor sentiment, shaped by both global and local factors, contributes significantly to silver price movements in Melbourne. The city’s vibrant financial scene, coupled with the increasing awareness of precious metals as an investment option, plays a role in shaping the demand for silver.
As investors in Melbourne closely monitor global economic indicators and geopolitical events, their reactions to these factors can create short-term fluctuations in the local silver market.
Embracing Evırı – A Paradigm Shift for a Sustainable Future
The idea of Evırı has emerged as a major factor innovating sustainable change in many fields as our world continues to develop and adapt. The unusual word “evr” stands for a paradigm shift that affects more than one industry and has far-reaching consequences. This article delves into the meaning of “evr” in the present day and the far-reaching effects it can have on the future.
Understanding the Concept of “evırı”
The concept of “evrr” embraces this idea of evolution and change indefinitely. It involves adapting to new circumstances, using change to your advantage, and making the most of the possibilities it brings. In essence, “evr” is not a final goal but a way of thinking that fosters never-ending development.
The Importance of “evırı” in Modern Society
Technological progress, cultural transformations, and environmental threats all contribute to the dynamic nature of today’s globe. To survive and succeed in these challenging times, “evrr” is a necessary compass bearing.
How “evırı” Impacts Various Industries
The concept of “evr” is having an impact on industries as diverse as IT and healthcare. In order to be competitive, businesses must embrace digital change and rethink their approaches to the market.
Challenges Faced in Implementing “evırı”
The process of putting “evrr” into practise is not simple. Negative emotions like dread, lethargy, and resistance to change can slow development. The “evrr” journey isn’t complete until these challenges are conquered.
The Role of Technology in Advancing “evırı”
To enable and speed up “evr,” technology is crucial. Businesses now have the means to constantly adapt and innovate because to advances in AI, big data, and automation.
Benefits of Embracing “evırı”
There are several upsides to embracing “evrr,” including better competitiveness, more efficiency, and higher levels of customer satisfaction. It’s the way to ensure long-term prosperity.
“evırı” and its Connection to Sustainability
The concept of “evr” is in harmony with the current worldwide emphasis on environmental responsibility. Businesses and individuals may help create a more sustainable environment by always seeking to improve and adapt.
Case Studies: Successful “evırı” Initiatives
Real-world examples of the benefits of this attitude may be shown by analysing successful “evr” efforts in a variety of fields.
Ethical Considerations Surrounding “evırı”
While “evrr” opens up a lot of doors, it also raises certain ethical questions that need answering. Adapting to change in a responsible and honourable manner is crucial.
The Future of “evırı”
The meaning of “evr” will develop further on its own. Anticipating and responding to emerging threats and opportunities is of paramount importance going ahead.
How Individuals Can Contribute to “evırı”
“evr” isn’t exclusive to formal institutions. This way of thinking may be adopted by individuals as a means of better adjusting to a dynamic reality.
Overcoming Resistance to Change
One major barrier to “evrr” is a person’s unwillingness to adapt. The key to success is learning how to circumvent this opposition.
Measuring the Success of “evırı”
Success in “evr” efforts may be gauged by monitoring KPIs, testing for adaptation, and calculating the long-term effects.
Unlocking potential and committing to a sustainable future in a dynamic environment requires the use of the word “evrr.” It has a profound effect on how we do business, how we create new things, and how successful we are. The “evr” mentality positions people and institutions at the front of progress, paving the way for a brighter future.
1. What does “evırı” mean?
The notion of “evr” stands for the ability to change and adapt indefinitely, therefore inspiring a never-ending cycle of development and progress.
2. Why is “evırı” important in modern society?
“evrr” is a tool for surviving and thriving in a world where everything is always changing.
3. How can technology support “evırı”?
Businesses now have the means to constantly innovate and adapt because to technological advancements such as AI and automation.
4. What are the ethical considerations related to “evırı”?
Ethical questions are raised by “evr”, therefore it is crucial to handle change in a responsible and honourable manner.
5. How can individuals contribute to “evırı”?
One way for people to adopt a “evr” attitude is to commit to lifelong learning and improvement in order to better navigate an ever-evolving environment.
Narwhals show physiological disruption in response to seismic survey ship noise
The reaction of narwhals to the loud noise from seismic air guns used in oil exploration involves a disruption of the normal physiological response to intense exercise as the animals try to escape the noise. The overall effect is a large increase in the energetic cost of diving while a paradoxically reduced heart rate alters the circulation of blood and oxygen.
“They’re swimming as hard as they can to get away, and yet their heart rate is not increasing—we think because of a fear response. This affects how much blood and oxygen can circulate, and that’s going to be problematic,” said Terrie Williams, a professor of ecology and evolutionary biology at UC Santa Cruz who led the new study.
Published July 8 in the Journal of Functional Ecology, the study provides the first look at the impact of seismic noise on the physiological responses of a deep-diving cetacean. According to Williams, the combination of extremely low heart rates, increased heart rate variability, and high-intensity exercise during deep dives presents a significant physiological challenge for narwhals, especially if the disruptions are prolonged as would be likely during extended oil exploration activities.
Narwhals live year-round in high Arctic waters where sea ice has helped isolate them from disturbance by humans for millions of years. But declines in polar sea ice are making the region more accessible to shipping, natural resource exploration, and other human activities.
In a previous study, Williams and her coauthors showed that narwhals released after entanglement in nets set by indigenous hunters showed a similar physiological response, with extremely low heart rates during intense exercise in a series of escape dives. The difference between a capture event and noise, Williams said, is the potential duration of the disturbance.
“When they escape from the nets, their heart rate comes back up to a more normal rate within three or four dives, but with the seismic ship moving through and the sound bouncing around, the escape response occurred over a longer period,” she said.
The researchers recorded not only extremely low heart rates during noise exposure, but also increased variability, with heart rates switching rapidly between extremely low rates associated with fear and fast rates associated with intense exercise. Reduced heart rate, or bradycardia, is a normal part of the mammalian dive response, but during normal dives the heart rate still increases with exercise. In addition, narwhals and other deep-diving marine mammals usually save energy by gliding rather than actively swimming as they descend to depth.
During noise exposure, the narwhals performed 80% less gliding during diving descents, their swimming strokes exceeded 40 strokes per minute, their heart rates dropped below 10 beats per minute, and their breathing at the surface was 1.5 times faster. Overall, this unusual reaction is very costly in terms of energy consumption, Williams said.
“Not only is the reaction costly in terms of the energy needed for diving, the escape time will also take away from time spent foraging for food and other normal behaviors,” she said.
The studies were conducted in Scoresby Sound on the east coast of Greenland, where coauthor Mads Peter Heide-Jørgensen, a research professor at the Greenland Institute of Natural Resources, has been studying the East Greenland narwhal population for more than a decade.
Williams’s group at UC Santa Cruz developed instruments that enable researchers to monitor the exercise physiology of marine mammals during dives. The instruments were attached to narwhals with suction cups and fell off after one to three days, floating to the surface where they could be recovered by the scientists.
Over the past two decades, noise from human activities such as military sonar has been linked to mass strandings of deep-diving cetaceans, mostly beaked whales. These deep-diving species are extremely difficult to study, and it was only through a partnership with indigenous hunters that Williams and Heide-Jørgensen’s teams were able to attach monitoring devices to narwhals.
“Most of the potential impacts on the animals take place underwater, so it’s really difficult to study,” Williams said. “We are fortunate to have this technology to show what’s happening at depth where these animals live in order to understand how their biology may be disrupted.”
In addition to Williams and Heide-Jørgensen, the coauthors of the paper include Susan Blackwell at Greeneridge Sciences, Outi Tervo and Eva Garde at the Greenland Institute of Natural Resources, Mikkel-Holger Sinding at University of Copenhagen, and Beau Richter at UC Santa Cruz. This work was supported by the U.S. Office of Naval Research, Greenland Institute of Natural Resources, the Environmental Agency for Mineral Resource Activities of the Government of Greenland, the Danish Ministry of Environment, and the Carlsberg Foundation.
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